Sodium dodecyl sulfate (SDS), 800-100/SDS 10% Solution, 880-550

Product Description:

SDS, i.e. Sodium dodecyl sulfate. Molecular Formula: C₁₂H₂₅O₄SNa, Molecular Weight: 288.38 g/mol, CAS: 151-21-3, Purity: ≥99%. This product is an anionic detergent and protein denaturant. It disrupts intra- and intermolecular hydrogen bonds of proteins and destroys their secondary and tertiary structures, capable of solubilizing most proteins. As a detergent, it also promotes the dissolution of certain lipophilic substances.

SDS is readily soluble in water with temperature-dependent solubility and tends to precipitate at low temperatures. It is commonly prepared as a 10% stock solution. It is widely used in SDS-PAGE electrophoresis for protein molecular weight determination, lysis of bacterial, cell and tissue samples, proteinase K digestion following biological sample lysis, and various protein denaturation-related experiments. It can dissociate nucleic acid-protein complexes during DNA extraction, disrupt cell membranes, and formulate prehybridization and hybridization solutions. In addition, SDS serves as one of the key components in multiple nucleic acid purification reagents and is applied in bacterial alkaline lysis and other related experiments.